منابع مشابه
Keeping score of antigraft T cells
Drugs that collapse the tumor vasculature by increasing the leakiness of tumor blood vessels are a new breed of chemotherapeutic agents, but how they worked was unknown. Now, Roberts et al. (page 1559) have determined the pathway and targets of one such vasculature-disrupting agent (VDA). They find that this drug does more than just increase leakiness. The VDA called DMXAA works well against se...
متن کاملThe CRABEL score--setting standards in maxillofacial medical note-keeping.
The CRABEL score (developed by Crawford, Beresford and Lafferty) was introduced for auditing medical note-keeping at Morriston Hospital in June 2001. Guidelines detailing the scoring system were issued to all clinicians in the maxillofacial unit. An auditor selected two sets of medical notes from each consultant's firm, giving an initial allocation of 100points/firm (50 points for each set of n...
متن کاملInduction of T Regulatory Subsets from Naïve CD4+ T Cells after Exposure to Breast Cancer Adipose Derived Stem Cells
Background: Adipose derived stem cells (ASCs) provoke the accumulation and expansion of regulatory T cells, leading to the modulation of immune responses in tumor microenvironment. Objective: To assess the effect of tumoral ASCs on the trend of regulatory T cells differentiation. Methods: Peripheral blood naïve CD4+ T cells were co-cultured with ASCs derived from breast cancer or normal breast ...
متن کاملKeeping wing cells in line
ell polarity in fly wing cells is set with extraordinary precision. Out of the distal end of each cell grows an actin-rich protrusion known as a wing hair. Although the wing contains over 30,000 epidermal cells, it produces this distal-specific hair pattern without error. C Wing hairs are locally aligned but lose distal orientation when the global Ft signal is disturbed. and colleagues indicate...
متن کاملT lymphocyte-mediated graft--antigraft reactivity during graft-versus-host reaction in vitro.
Spleen organ cultures were prepared from lethally irradiated mice that had been injected with allogeneic bone marrow, with or without lymph node cells. These cultures were used in the analysis of graft-versus-host reactions (GVHR) in vitro. It was found that donor-derived T lymphocytes, which had been grown in an allogeneic spleen, prevented hemopoietic progenitor cells (colony-forming cells, C...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 2007
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.2047iti4